Jake And Maggie Gyllenhaal (A Dangerous Woman, Homegrown, Donnie Darko)
Oscar nominee Jake Gyllenhaal and his twice-nominated older sister, Maggie, are in three movies together: 1993’s A Dangerous Woman, 1998’s Homegrown (both were directed by their father, Stephen), and the eventual sci-fi cult classic, Donnie Darko, in 2001.
Jeff And Beau Bridges (The Fabulous Baker Boys)
Oscar winner Jeff Bridges and his older brother, Beau, also played siblings in The Fabulous Baker Boys - a 1989 comedy in which the titular musicians become rivals after teaming up with a beautiful aspiring singer (Michelle Pfieffer).
Kate And Rooney Mara (Urban Legends: Bloody Mary)
Kate Mara of the House of Cards cast led the 2005 straight-to-video slasher, Urban Legends: Bloody Mary, in which her younger sister, Nightmare Alley’s Rooney Mara, made her acting debut.
Andrew, Owen, And Luke Wilson (Bottle Rocket, The Royal Tenenbaums)
Owen Wilson and his younger sibling, Luke have also acted alongside their eldest brother, Andrew, in 1996’s Bottle Rocket and The Royal Tenenbaums from 2001 - both of which Owen also co-wrote with director Wes Anderson.
Dylan And Cole Sprouse (Various)
Twin brothers Dylan and Cole Sprouse (the latter of which went on to join the Riverdale cast) have shared the same role in several TV shows (most notably Grace Under Fire) and movies (such as Big Daddy with Adam Sandler) and have played siblings just as often,
Tia, Tamera, And Tahj Mowry (Sister, Sister, Smart Guy, Seventeen Again)
Twin sisters Tia and Tamera Mowry have shared the screen with their little brother, Tahj, several times - most notably as guest stars on each other’s respective sitcoms, Sister, Sister and Smart Guy, and in the 2000 Showtime original movie, Seventeen Again.
Hilary And Haylie Duff (Various)
Haylie Duff would appear on three episodes of her younger sister, Hilary’s, Disney Channel show, Lizzie McGuire, and provided the singing voice of Isabella Parigi in the theatrical spin-off before they both played a singing group on an episode of American Dreams,
Aly And AJ Michalka (Various)
Singer-songwriter duo Aly and AJ Michalka first shared the screen in the 2006 Disney Channel original movie Cow Belles as sisters, again in the MTV original Super Sweet 16: The Movie the next year as rivals, followed by three episodes of Aly’s CW series Hellcats in 2011 as half-sisters.